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My laboratory investigates the molecular mechanisms of initial bacterial attachment to teeth, tissue, or biomaterial surfaces in the mouth. We try to unravel the molecular mechanisms of how glycoproteins in saliva or on host cells are recognized by glycan-binding microbial adhesins. It is our long-term goal to better understand the modulating role of saliva in supporting colonization of the human oral cavity by a benign commensal microbiota, and in host defense against pathogenic microorganisms. More recently, our research involves the investigation of evolutionary mechanisms that have shaped host-microbial interactions in the human mouth.

A more detailed description of our current research activities can be found on the following website: www.ruhl-lab.org
Education and Training:
•    Professor (C3), Operative Dentistry and Periodontology, Universität Regensburg (2004)
•    Privatdozent, venia legendi, Operative Dentistry and Periodontology, Universität Regensburg, (venia legendi) (2000)
•    PhD, Dr. med. dent., Georg-August-Universität Göttingen, Magna Cum Laude (1988)
•    DDS, Dentistry, Georg-August-Universität Göttingen (1984)
Employment:
•    Associate Chair, Oral Biology, University at Buffalo (2019-present)
•    Adjunct Professor, Microbiology and Immunology, University at Buffalo (2016-present)
•    Professor, Oral Biology, University at Buffalo (2015-present)